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dc.contributor.authorMelika Ghelichpouren_US
dc.contributor.authorAli Taheri Mirghaeden_US
dc.contributor.authorMahmoud A.O. Dawooden_US
dc.contributor.authorSeyed Hossein Hoseinifaren_US
dc.contributor.authorHien Van Doanen_US
dc.description.abstract© 2020 John Wiley & Sons Ltd The present study aimed to assess the benefits of dietary olive (Olea europea) leaf extract (OLE) on haematological, biochemical and antioxidant parameters in the blood and livers of common carp (Cyprinus carpio) exposed to the pesticide Danitol®. Four treatments were carried out: (a) fish fed the control diet for 37 days (control); (b) fish fed the control diet for 30 days, followed by 7 days of exposure to 0.05 mg/L Danitol®; (c) fish fed the E1 diet for 30 days, followed by 7 days of exposure to 0.05 mg/L Danitol® (1 g/kg OLE); and (d) fish fed the E2 diet for 30 days, followed by seven days of exposure to 0.05 mg/L Danitol® (2 g/kg OLE). Exposure to Danitol® significantly decreased red blood count (RBC), haematocrit, haemoglobin, plasma and hepatic catalase (CAT), and superoxide dismutase (SOD) activities. However, the pesticide increased plasma alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and plasma and hepatic malondialdehyde (MDA) contents. The RBC showed lower resistance against hypotonic osmotic shock, as established by the osmotic fragility test. OLE administration restored the changes caused by Danitol®, of which the most pronounced effects were observed in the fish fed 2 g/kg OLE. We may conclude that Danitol® exposure causes oxidative stress, yet provide protection against numerous adverse effects through the supplementation of olive oil extract (OLE), resulting in a higher red blood cell count.en_US
dc.subjectAgricultural and Biological Sciencesen_US
dc.titleAlteration of haematological and antioxidant parameters in common carp (Cyprinus carpio) fed olive (Olea europea) leaf extract after exposure to Danitol<sup>®</sup>en_US
article.title.sourcetitleAquaculture Researchen_US Universityen_US University of Agricultural Sciences and Natural Resourcesen_US of Tehranen_US Mai Universityen_US
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