Porous bioceramic made from cow bone powder mixed calcium phosphate glass: Clinical trial

Abstract

© 2020 Trans Tech Publications Ltd, Switzerland. Our objective is invention of new medical products in Thailand by Thai scientists, for human bone substitute, from cow bone. In the previous research experiments, the cow bone-calcium phosphate glass composites had adequate scientific properties to be used as medical objects including, 95% of principal molecules were inorganic hydroxyapatite, no contaminating dangerous heavy metal over standard limits (cadmium, arsenic, mercury, lead), high vertical compressive strength (more than 400 kg/cm2 ), and no adverse reactions inside the laboratory animals. In this research, we made cranialfixator buttons from bovine bone-calcium phosphate glass composites, intended for neurosurgical skull closure, tested in 10 patients and follow up for at least 6 months. The results revealed that our inventions have easily performance, really effectiveness, and entirely non-complications.