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Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/70205
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dc.contributor.authorSongyot Anuchapreedaen_US
dc.contributor.authorRiki Anzawaen_US
dc.contributor.authorNatsima Viriyaadhammaaen_US
dc.contributor.authorWaranya Neimkhumen_US
dc.contributor.authorWantida Chaiyanaen_US
dc.contributor.authorSiriporn Okonogien_US
dc.contributor.authorToyonobu Usukien_US
dc.date.accessioned2020-10-14T08:25:36Z-
dc.date.available2020-10-14T08:25:36Z-
dc.date.issued2020-07-15en_US
dc.identifier.issn14643405en_US
dc.identifier.other2-s2.0-85086355236en_US
dc.identifier.other10.1016/j.bmcl.2020.127256en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85086355236&origin=inwarden_US
dc.identifier.urihttp://cmuir.cmu.ac.th/jspui/handle/6653943832/70205-
dc.description.abstractCopyright © 2020 Elsevier Ltd. All rights reserved. The leaves of the kaffir lime (Citrus hystrix) are commonly used in cuisine and folk medicine. The aim of this study was to isolate a bioactive compound in kaffir lime leaves and characterize its biological activity. The compound was isolated from a hexane fractional extract and identified as agrostophillinol. This is the first report of agrostophillinol isolated from kaffir lime leaves. In terms of cytotoxicity, agrostophillinol exhibited IC50 values of 36.27 ± 7.30 and 53.44 ± 10.63 μg/mL against EoL-1 and HL60 cells, respectively. Agrostophillinol also exhibited potent anti-inflammatory activity, significantly inhibiting IL-6 secretion.en_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectChemistryen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleIsolation and biological activity of agrostophillinol from kaffir lime (Citrus hystrix) leavesen_US
dc.typeJournalen_US
article.title.sourcetitleBioorganic & medicinal chemistry lettersen_US
article.volume30en_US
article.stream.affiliationsHuachiew Chalermprakiet Universityen_US
article.stream.affiliationsSophia Universityen_US
article.stream.affiliationsChiang Mai Universityen_US
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