Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/70203
Title: Fragranol A: A new class of spiro-triflavanoid hybrid with an unprecedented carbon skeleton from Anneslea fragrans
Authors: Ashraf M. Omar
Sijia Sun
Min Jo Kim
Ahmed M. Tawila
Dya Fita Dibwe
Ampai Phrutivorapongkul
Naoki Toyooka
Suresh Awale
Keywords: Biochemistry, Genetics and Molecular Biology
Chemistry
Pharmacology, Toxicology and Pharmaceutics
Issue Date: 16-Jul-2020
Abstract: © 2020 Elsevier Ltd Phytochemical investigation of Anneslea fragrans twigs resulted in the discovery of fragranol A (1), a new class of structurally challenging and sterically hindered “spiro-triflavanoid” type compound possessing an unprecedented carbon skeleton. Fragranol A (1) consists of 45 carbons having six chiral carbons, including two spiro-chiral centers. Structural elucidation of 1 was achieved by HRFABMS, 1D and 2D NMR, analysis of spatial anisotropic effects, and quantum ECD calculations. A plausible biogenetic pathway of 1 is also proposed.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85086176895&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/70203
ISSN: 18733581
00404039
Appears in Collections:CMUL: Journal Articles

Files in This Item:
There are no files associated with this item.


Items in CMUIR are protected by copyright, with all rights reserved, unless otherwise indicated.