Limonoids and carbazole alkaloids from the twigs of Chalcas siamensis Tanaka

Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/70088

Title:	Limonoids and carbazole alkaloids from the twigs of Chalcas siamensis Tanaka
Authors:	Sirada Boonyaketgoson Vatcharin Rukachaisirikul Souwalak Phongpaichit Kongkiat Trisuwan
Authors:	Sirada Boonyaketgoson Vatcharin Rukachaisirikul Souwalak Phongpaichit Kongkiat Trisuwan
Keywords:	Agricultural and Biological Sciences;Biochemistry, Genetics and Molecular Biology;Chemistry
Issue Date:	1-Jan-2020
Abstract:	© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. One new limonoid, named siamensinolide (1), together with two known limonoids (2 and 3) and eight carbazole alkaloids (4–11) were isolated from the twigs of Chalcas siamensis Tanaka. Their structures were elucidated by spectroscopic methods, mainly 1D and 2D NMR spectroscopy. O-methylclausenolide (2) displayed strong cytotoxicity against A2780 cell lines with the IC50 value of 9.2 µM, while clausenolide (3) exhibited strong antibacterial activity against methicillin-resistant Staphylococcus aureus with the MIC value of 0.5 µg/mL.
URI:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85086018043&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/70088
ISSN:	14786427 14786419
Appears in Collections:	CMUL: Journal Articles

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