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Title: | Actinomycins Produced by Streptomyces lichenis LCR6-01T and its Antibacterial Activity |
Authors: | Pawina Kanchanasin Patcharin Saeng-in Takuji Nakashima Hirotaka Matsuo Yōko Takahashi Somboon Tanasupawat |
Authors: | Pawina Kanchanasin Patcharin Saeng-in Takuji Nakashima Hirotaka Matsuo Yōko Takahashi Somboon Tanasupawat |
Keywords: | Streptomyces lichenis;antimicrobial activity;actinomycin;mass spectrometry |
Issue Date: | 2020 |
Publisher: | Faculty of Science, Chiang Mai University |
Citation: | Chiang Mai Journal of Science 47,5 (Sep 2020), p.864-871 |
Abstract: | A new actinomycete species, Streptomyces lichenis LCR6-01T was isolated from lichen collected in Chiang Rai province, Thailand. On the course of screening for antimicrobial activity, the culture broth of strain LCR6-01T exhibited antibacterial activity against Bacillus subtilis ATCC 6633, Kocuria rhizophila ATCC 9341, Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922 (inhibition zone 14.7 0.6 - 23.0 0.9 mm). The culture extracts analyzed by liquid chromatographyelectrospray ionization-mass spectrometry (LC-ESI-MS) and the physicochemical properties of secondary metabolites were searched in database. The antibacterial agents were detected as actinomycins which contained 3 analogs of Au7a, D, and D 43β. |
Description: | The Chiang Mai Journal of Science is an international English language peer-reviewed journal which is published in open access electronic format 6 times a year in January, March, May, July, September and November by the Faculty of Science, Chiang Mai University. Manuscripts in most areas of science are welcomed except in areas such as agriculture, engineering and medical science which are outside the scope of the Journal. Currently, we focus on manuscripts in biology, chemistry, physics, materials science and environmental science. Papers in mathematics statistics and computer science are also included but should be of an applied nature rather than purely theoretical. Manuscripts describing experiments on humans or animals are required to provide proof that all experiments have been carried out according to the ethical regulations of the respective institutional and/or governmental authorities and this should be clearly stated in the manuscript itself. The Editor reserves the right to reject manuscripts that fail to do so. |
URI: | https://epg.science.cmu.ac.th/ejournal/dl.php?journal_id=11187 http://cmuir.cmu.ac.th/jspui/handle/6653943832/69900 |
ISSN: | 2465-3845 |
Appears in Collections: | CMUL: Journal Articles |
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