Diagnostic biomarker SDMA for kidney disease in dogs and cats

Abstract

Kidney disease is one of the most commonly found in dogs and cats. The Golden standard diagnosis for kidney disease in Veterinary Medicine is the veterinarians identify renal function by measuring glomerular filtration rate (GFR), indirectly with increased serum creatinine and blood urea nitrogen (BUN) are routinely diagnosed with kidney disease. But some factors have interfered with by these profiles such as body mass condition, high protein diet, in respectively. These routine profiles can detect when the kidney function had decreased more than 75% Although this article reviews the newest renal biomarker; Symmetric dimethylarginine (SDMA) for diagnostic biomarker in kidney disease. It can detect at kidney function had decreased more than 25%, which is a good biomarker for the earliest stage of kidney disease. This article will show the advantages of SDMA, can detect at the early stage of kidney disease before the serum creatinine was increasing. The application of this renal biomarker for detection at the early stage of kidney disease. It means that we can recover and correct the animals from loss of the kidney to be normal and reduce the progressions of kidney disease to a chronic stage in dogs and cats.