Outcome treatment of canine brain tumors at Kasetsart University Veterinary Teaching Hospital

Abstract

The treatment outcomes in 48 dogs with brain tumors that were diagnosed by Magnetic Resonance Imaging (MRI) and underwent surgery, radiation therapy and palliative treatment at Kasetsart University Veterinary Teaching Hospital were studies by survival analysis. The Kaplan-Meier curve was used to estimate overall survival probabilities. Log rank test and Cox regression analysis were used to assess factor related to treatment outcome. Six dogs underwent surgery, 12 dogs received radiation therapy and 30 dogs received palliative treatment. The median survival time for all dogs was 91 days. Median survival time of dogs receiving: 1) surgery, 2) radiation therapy and 3) palliative treatment were 166, 161 and 35 days, respectively. Median survival time of radiation group was significantly higher than symptomatic management group (P < 0.05). No significant difference in survival time was found between dogs with surgically treatment and radiation treatment. MR feature as necrosis show significance as prognostic variable in this study.