Please use this identifier to cite or link to this item:
|Title:||Outcome of surgical and radiation therapy treatment of grade II meningiomas: A single institution experience|
|Other Titles:||ผลการรักษาโรคเนื้องอกเยื่อหุ้มสมองระดับ 2 ด้วยการผ่าตัดและการฉายรังสีในสถาบันที่วิจัยเพียงสถาบันเดียว|
|Keywords:||WHO grade II meningiomas|
adjuvant radiation therapy
|Publisher:||Faculty of Medicine, Chiang Mai University|
|Citation:||Chiang Mai Medical Journal 57, 3 (July-Sept 2019), 135-141|
|Abstract:||Objective To evaluate local control and survival rates with two different treatment modalities: surgery alone and surgery plus adjuvant radiation therapy (RT). Methods Cases of 104 patients diagnosed with grade II meningiomas between 2004 and 2014 were retrospectively reviewed. Of those, 68 patients had complete medical records. For inclusion in this study, we required a follow-up period of more than 2 years. Age at diagnosis, initial tumor size, tumor location, extent of resection and adjuvant RT were categorized to identify possible parameters that may have affected the outcome of this disease. Result Thirty-seven patients (54%) received surgery alone while 31 patients (46%) received adjuvant RT. The 2-year and 5-year rates of local control (LC) were 94% and 87%, respectively. No correlation was found between other parameters and recurrence of tumors. Patients in our study who received adjuvant RT had signi fi cant lower overall survival rate (p=0.044). The 2-year overall survival (OS) was 99% and 5-year OS was 93%. Conclusion Tumor control and survival were found to be excellent in this retrospective study. Adjuvant RT did not in fl uence local control, but was statistically associated with lower survival rates. Further prospective study should be performed to clarify the management of grade II meningiomas.|
|Description:||Chiang Mai Medical Journal (Formerly Chiang Mai Medical Bulletin) is an official journal of the Faculty of Medicine, Chiang Mai University. It accepts original papers on clinical and experimental research that are pertinent in the biomedical sciences. The Journal is published 4 issues/year (i.e., Mar, Jun, Sep, and Dec).|
|Appears in Collections:||CMUL: Journal Articles|
Files in This Item:
There are no files associated with this item.
Items in CMUIR are protected by copyright, with all rights reserved, unless otherwise indicated.