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dc.contributor.authorSupeera Nootchanaten_US
dc.contributor.authorWisansaya Jaikeandeeen_US
dc.contributor.authorPatrawadee Yaiwongen_US
dc.contributor.authorChutiparn Lertvachirapaiboonen_US
dc.contributor.authorKazunari Shinboen_US
dc.contributor.authorKeizo Katoen_US
dc.contributor.authorSanong Ekgasiten_US
dc.contributor.authorAkira Babaen_US
dc.description.abstract© 2019 American Chemical Society. In this study, we demonstrate a simple and efficient method to fabricate miniature surface plasmon resonance (SPR) sensor chips by using confined sessile drop technique. A liquid optical adhesive (NOA 61) was dropped on the circular flat surface of cylindrical substrates made of poly(dimethylsiloxane) (PDMS). The formation of hemispherical optical prisms was accomplished by taking advantage of the sharp edges of cylindrical PDMS substrates that prevented the overflow of liquid NOA 61 at the edge of substrates. The size of the hemispherical optical prisms can be controlled by changing the diameter of the cylindrical PDMS substrates. After UV curing, the SPR sensor chips were obtained by the deposition of 3 nm thick chromium and 47 nm thick gold on the flat side of the prisms. The fabricated miniature SPR sensor chips were then mounted on a three-dimensional-printed flow cell to complete the microfluidic SPR sensor module. The miniature SPR sensor chips provided a comparable sensitivity to the conventional high-refractive-index glass SPR chips. To demonstrate the detection capability of nanometer-sized materials, we applied the miniature microfluidic SPR system for monitoring the deposition of layer-by-layer ultrathin films of poly(diallyldimethylammonium chloride)/poly(sodium 4-styrenesulfonate) and for detecting human immunoglobulin G.en_US
dc.subjectMaterials Scienceen_US
dc.titleFabrication of Miniature Surface Plasmon Resonance Sensor Chips by Using Confined Sessile Drop Techniqueen_US
article.title.sourcetitleACS Applied Materials and Interfacesen_US
article.volume11en_US Universityen_US Universityen_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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