Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/65665
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dc.contributor.authorPensak Jantrawuten_US
dc.contributor.authorJuthamart Bunrueangthaen_US
dc.contributor.authorJuthamart Suerthongen_US
dc.contributor.authorNutthapong Kantrongen_US
dc.date.accessioned2019-08-05T04:38:38Z-
dc.date.available2019-08-05T04:38:38Z-
dc.date.issued2019-05-01en_US
dc.identifier.issn19961944en_US
dc.identifier.other2-s2.0-85066871103en_US
dc.identifier.other10.3390/ma12101628en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85066871103&origin=inwarden_US
dc.identifier.urihttp://cmuir.cmu.ac.th/jspui/handle/6653943832/65665-
dc.description.abstract© 2019 by the authors. In this study, hydrogel films composed of low methoxyl pectin (LMP), gelatin, and carboxymethyl cellulose (CMC) were fabricated. Glycerin was used as a plasticizer while glutaraldehyde (Glu) and calcium chloride (CaCl2) were used as crosslinking agents in film preparation. Hydrogel films were morphologically characterized and evaluated for mechanical properties. In addition, the investigations for fluid uptake ability, water retention capacity, water vapor transmission rate, and integrity value of the invented films were performed. The results showed that F-Glu-Ca-G30 film demonstrated superior properties when compared to other prepared films. It demonstrated a high percentage of elongation at break (32.80%), fluid uptake ability (88.45% at 2 h), water retention capacity (81.70% at 2 h), water vapor transmission rate (1889 g/m2/day), and integrity value (86.42%). F-Glu-Ca-G30 film was subsequently selected for 10% w/w povidone iodine (PI) loading and tested for anti-Staphylococcus aureus activity using an agar diffusion assay. Notably, F-Glu-Ca-G30-PI film demonstrated a dramatic ability to inhibit microbial growth, when compared to both a blank film and iodine solution control. Our LMP/gelatin/CMC hydrogel film promises to be an effective dressing material with high fluid absorption capacity, fluid holding ability, and water vapor transmission rate. Incorporation of antibiotics such as povidone iodine into the films conferred its antimicrobial property thereby highlighting its potential dermatological use. However, further clinical studies of the application of this hydrogel film as wound dressing material is recommended.en_US
dc.subjectMaterials Scienceen_US
dc.titleFabrication and characterization of low methoxyl pectin/gelatin/carboxymethyl cellulose absorbent hydrogel film for wound dressing applicationsen_US
dc.typeJournalen_US
article.title.sourcetitleMaterialsen_US
article.volume12en_US
article.stream.affiliationsKhon Kaen Universityen_US
article.stream.affiliationsChiang Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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