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Title: Differentiation of pituitary macroadenoma and craniopharyngioma in adult Patients: MRI fi ndings
Other Titles: การแยก pituitary macroadenoma และ craniophagyngioma ในผู้ป่วยผู้ใหญ่จากภาพเอกซเรย์คลื่นแม่เหล็กไฟฟ้า
Authors: Panupong Radchauppanone
Kanokporn Oranratanachai
Salita Angkurawaranon
Kittisak Unsrisong
Songkiet Suwansirikul
Issue Date: 2016
Publisher: Chiang Mai University. Faculty of Medicine
Abstract: Objective To compare the MRI fi ndings between pituitary macroadenoma and craniopharyngioma. Methods This retrospective study was conducted at our university Hospital. Patient data between January 2006 to June 2014 were reviewed. Pathological proof of pituitary macroadenoma 61 patients and other 10 patients of craniopharyngioma were included in the study. The patient data were categorized into gender and age. MRI fi ndings analysed the tumor size, shape, component, adjacent brain edema, cavernous sinus invasion, sellar widening, presence of posterior T1-weighted bright spot, presence of normal pituitary gland, signal intensity of solid/cystic components on T1 and T2-weighted images and pattern of enhancement. Results A snowman or ovoid shape with solid component, presence of sellar widening and posterior T1 bright spot were suggestive of pituitary macroadenoma (p<0.05). A lobulated shape with cystic component, presence of adjacent brain edema, epicenter of the tumor in suprasellar region which could be separable from the normal pituitary gland and presence of rim enhancement were suggestive of craniopharyngioma (p<0.05). Conclusion MRI fi ndings were helpful to distinguish between pituitary macroadenoma and craniopharyngioma by using tumor shape, component, sellar widening, presence of posterior T1 brightspot, adjacent brain edema, epicenter of the tumor in suprasellar region which could be separable from the normal pituitary gland and presence of rim enhancement.
Description: Chiang Mai Medical Journal (Formerly Chiang Mai Medical Bulletin) is an official journal of the Faculty of Medicine, Chiang Mai University. It accepts original papers on clinical and experimental research that are pertinent in the biomedical sciences. The Journal is published 4 issues/year (i.e., Mar, Jun, Sep, and Dec). Original articles, review articles, brief reports, case reports, and miscellany (editorials, perspectives, opinions, and letters to the editor) are welcome. All manuscripts submitted to Chiang Mai Medical Journal must not have been previously published (except in abstract form) or under consideration for publication elsewhere. Each submitted article will be reviewed by two referrees or more. Following publication, Chiang Mai Medical Journal reserves the copyright of all published materials and such materials may not be reproduced in any form without written permission from Chiang Mai Medical Journal. We strongly recommend that authors follow the guideline in manuscript preparation below. Failure to comply with the instruction will result in delay the processing of your paper
ISSN: 0125-5983
Appears in Collections:CMUL: Journal Articles

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