Please use this identifier to cite or link to this item:
Title: Mechanochemical synthesis of primary amides from carboxylic acids using TCT/NH<inf>4</inf>SCN
Authors: Subin Jaita
Wong Phakhodee
Neeranuch Chairungsi
Mookda Pattarawarapan
Keywords: Biochemistry, Genetics and Molecular Biology
Pharmacology, Toxicology and Pharmaceutics
Issue Date: 26-Sep-2018
Abstract: © 2018 A facile and effective approach toward the synthesis of primary amides from carboxylic acids has been developed. In the presence of 2,4,6-trichloro-1,3,5-triazine, a combination of ammonium thiocyanate and potassium carbonate led to the rapid conversion of carboxylic acids into the corresponding amides within five minutes grinding at room temperature. The use of ammonium thiocyanate as the amine source is unprecedented and exclusive formation of primary amides is observed only under the liquid-assisted grinding conditions.
ISSN: 18733581
Appears in Collections:CMUL: Journal Articles

Files in This Item:
There are no files associated with this item.

Items in CMUIR are protected by copyright, with all rights reserved, unless otherwise indicated.