Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/62562
Title: Mechanochemical synthesis of primary amides from carboxylic acids using TCT/NH<inf>4</inf>SCN
Authors: Subin Jaita
Wong Phakhodee
Neeranuch Chairungsi
Mookda Pattarawarapan
Keywords: Biochemistry, Genetics and Molecular Biology
Chemistry
Pharmacology, Toxicology and Pharmaceutics
Issue Date: 26-Sep-2018
Abstract: © 2018 A facile and effective approach toward the synthesis of primary amides from carboxylic acids has been developed. In the presence of 2,4,6-trichloro-1,3,5-triazine, a combination of ammonium thiocyanate and potassium carbonate led to the rapid conversion of carboxylic acids into the corresponding amides within five minutes grinding at room temperature. The use of ammonium thiocyanate as the amine source is unprecedented and exclusive formation of primary amides is observed only under the liquid-assisted grinding conditions.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85052623821&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/62562
ISSN: 18733581
00404039
Appears in Collections:CMUL: Journal Articles

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