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Title: Spectrum of bone tumors in Chiang Mai University Hospital, Thailand according to WHO classification 2002: A study of 1,001 cases
Authors: Jongkolnee Settakorn
Suree Lekawanvijit
Olarn Arpornchayanon
Samreung Rangdaeng
Pramote Vanitanakom
Sarawut Kongkarnka
Ruangrong Cheepsattayakorn
Charin Ya-In
Paul S. Thorner
Keywords: Medicine
Issue Date: 21-Jul-2006
Abstract: Objective: The aim of the present study was to determine the spectrum, frequency and demographics of bone tumors. Material and Method: A retrospective study of the 1,001 bone tumor specimens from the files at the Pathology Department of the Chiang Mai University Hospital, Thailand from 2000 to 2004. Results: From the study, 41 were non-neoplastic mass lesions, and 960 were neoplastic, with 856 (89%) as primary and 104 (11%) as metastatic tumors. In the primary tumor group, 654 (76%) cases were of hematologic origin, and 202 (24%) were non-hematologic. The most common benign bone tumors were giant cell tumor (n = 37), osteochondroma (n = 25), and chondroma (n = 15). The most common malignant bone tumors were lymphoma-leukemia (n = 583), metastatic malignancy (n = 104), plasma cell myeloma (n = 71), and osteosarcoma (n = 58). Conclusion: The present study showed a higher frequency of osteosarcoma (68%), lower frequencies of chondrosarcoma (12%) and Ewing sarcoma (4%) among primary non-hematologic malignant bone tumors when compared with similar studies based on Western patients. Whether these differences reflect differences in the ethnic population or in practice patterns remains to be determined.
ISSN: 01252208
Appears in Collections:CMUL: Journal Articles

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