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dc.contributor.authorSitthicha Siriareeen_US
dc.contributor.authorJatupol Srisomboonen_US
dc.contributor.authorChumnan Kietpeerakoolen_US
dc.contributor.authorSurapan Khunamornpongen_US
dc.contributor.authorSumalee Siriaunkgulen_US
dc.contributor.authorApaporn Natpratanen_US
dc.contributor.authorSumon Pratheapjarusen_US
dc.contributor.authorAmornrat Futemwongen_US
dc.contributor.authorUraporn Chantarasenawongen_US
dc.description.abstractThis study was undertaken to evaluate the incidence and severity of residual lesions in women featuring highgrade squamous intraepithelial lesion (HSIL) histology with endocervical cone margin involvement after the loop electrosurgical excision procedure (LEEP). The medical records of women undergoing LEEP at Chiang Mai University Hospital between October 2004 and February 2006 were retrospectively reviewed and 74 cases were identified. Nineteen women were excluded because of loss to follow-up. The remaining 4 were referred to other hospitals and 2 declined re-excision, leaving a study population of 55 women for analysis. Mean age ± SD of the patients was 48.5 ± 8.9 years. Residual lesions were noted in 26 (47.3%, 95%CI= 33.7 to 61.2). Four (7.3%) had unrecognized invasive cervical carcinoma in subsequent specimens. In conclusion, approximately half of women with positive endocervical cone margins after LEEP for HSIL histology have residual disease. Repeat diagnostic excision is recommended for evaluation of lesions and severity.en_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.titleHigh-grade squamous intraepithelial lesion with endocervical cone margin involvement after cervical loop electrosurgical excision: What should a clinician do?en_US
article.title.sourcetitleAsian Pacific Journal of Cancer Preventionen_US
article.volume7en_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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