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Title: Use of Potentially Inappropriate Medications in People With Dementia in Vietnam and Its Associated Factors
Authors: Tuan Anh Nguyen
Thang Pham
Huyen Thi Thanh Vu
Thanh Xuan Nguyen
Trinh Thi Vu
Binh Thi Thanh Nguyen
Ngoc Quynh Nguyen
Binh Thanh Nguyen
Binh Thanh Nguyen
Tam Ngoc Nguyen
Sinh Viet Phan
Anh Trung Nguyen
Tuan Le Pham
Ha Thu Dang
Lisa Kalisch-Ellett
Marianne Gillam
Nicole Pratt
Sun Qiang
Haipeng Wang
Tipaporn Kanjanarach
Mohamed Azmi Ahmad Hassali
Zaheer Ud Din Babar
Asrenee Ab Razak
Dujrudee Chinwong
Elizabeth E. Roughead
Keywords: Medicine
Issue Date: 1-Jan-2018
Abstract: © 2018, The Author(s) 2018. This study examined the use of potentially inappropriate medicines that may affect cognition (PIMcog) in people with dementia and its associated factors. Medical records of all outpatients with dementia attending a tertiary hospital in Vietnam between January 1, 2015, and December 31, 2016, were examined. Medicine use was assessed against a list of PIMcog. Variables associated with having a PIMcog were assessed using a multiple logistic regression. Of the 128 patients, 41% used a PIMcog, 39.1% used cholinesterase inhibitors (CEIs) concomitantly with anticholinergics, and 18% used antipsychotics. The number of hospital visits (adjusted odds ratio [OR]: 1.08; 95% confidence interval [CI]: 1.02-1.16) and number of treating specialists (adjusted OR: 0.61; 95% CI: 0.45-0.83) were associated with PIMcog use. This study highlights a high-level use of medicines that can further impair cognition or reduce the effectiveness of CEIs in people with dementia. Efforts to improve quality use of medicines for this population are warranted.
ISSN: 19382731
Appears in Collections:CMUL: Journal Articles

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