Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorChammari Pothiporen_US
dc.contributor.authorChutiparn Lertvachirapaiboonen_US
dc.contributor.authorKazunari Shinboen_US
dc.contributor.authorKeizo Katoen_US
dc.contributor.authorFutao Kanekoen_US
dc.contributor.authorKontad Ounnunkaden_US
dc.contributor.authorAkira Babaen_US
dc.description.abstract© 2018 The Japan Society of Applied Physics. An electrochemically synthesized graphene oxide (GO)/poly(3,4-ethylenedioxythiophene) (PEDOT)/poly(styrene sulfonate) (PSS) thin film-based electrochemical surface plasmon resonance (EC-SPR) sensor chip was developed and employed for the detection of human immunoglobulin G (IgG). GO introduced the carboxylic group on the film surface, which also allowed electrochemical control, for the immobilization of the anti-IgG antibody via covalent bonding through amide coupling reaction. The SPR sensitivity of the detection was improved under the control by applying an electrochemical potential, by which the sensitivity was increased by the increment in applied potential. Among the open-circuit and different applied potentials in the range of -1.0 to 0.50 V, the EC-SPR immunosensor at an applied potential of 0.50 V exhibited the highest sensitivity of 6.08 × 10-3mL μg-1cm-2and linearity in the human IgG concentration range of 1.0 to 10 μg mL-1with a relatively low detection limit of 0.35 μg mL-1. The proposed sensor chip is promising for immunosensing at the physiological level.en_US
dc.subjectPhysics and Astronomyen_US
dc.titleDevelopment of graphene oxide/poly(3,4-ethylenedioxythiophene)/poly(styrene sulfonate) thin film-based electrochemical surface plasmon resonance immunosensor for detection of human immunoglobulin Gen_US
article.title.sourcetitleJapanese Journal of Applied Physicsen_US
article.volume57en_US Universityen_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

Files in This Item:
There are no files associated with this item.

Items in CMUIR are protected by copyright, with all rights reserved, unless otherwise indicated.