Please use this identifier to cite or link to this item:
|Title:||Acetylcholinesterase inhibitory activity of chemical constituents isolated from Miliusa thorelii|
Stephen G. Pyne
Thunwadee Limtharakul (née Ritthiwigrom)
|Keywords:||Agricultural and Biological Sciences|
Biochemistry, Genetics and Molecular Biology
|Abstract:||© 2017 Phytochemical Society of Europe Two new dihydrooxoprotoberberine alkaloids; miliusathorines A (1) and B (2), a new natural flavone, miliusathorone (3), together with twenty-two known compounds (4–25) were isolated from the combined stem and root extract and the leaf extract of Miliusa thorelii. The structures of all isolated compounds were elucidated by spectroscopic methods and mass spectrometry. All compounds were evaluated for their acetylcholinesterase activities. Miliusathorine A (1) and norushisunine had the best AChE inhibitory activities, however these were weak inhibitors when compared to the standard galantamine.|
|Appears in Collections:||CMUL: Journal Articles|
Files in This Item:
There are no files associated with this item.
Items in CMUIR are protected by copyright, with all rights reserved, unless otherwise indicated.