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dc.contributor.authorU. Raghavendraen_US
dc.contributor.authorU. Rajendra Acharyaen_US
dc.contributor.authorAnjan Gudigaren_US
dc.contributor.authorJen Hong Tanen_US
dc.contributor.authorHamido Fujitaen_US
dc.contributor.authorYuki Hagiwaraen_US
dc.contributor.authorFilippo Molinarien_US
dc.contributor.authorPailin Kongmebholen_US
dc.contributor.authorKwan Hoong Ngen_US
dc.description.abstract© 2017 Elsevier B.V. Thyroid is a small gland situated at the anterior side of the neck and one of the largest glands of the endocrine system. The abrupt cell growth or malignancy in the thyroid gland may cause thyroid cancer. Ultrasound images distinctly represent benign and malignant lesions, but accuracy may be poor due to subjective interpretation. Computer Aided Diagnosis (CAD) can minimize the errors created due to subjective interpretation and assists to make fast accurate diagnosis. In this work, fusion of Spatial Gray Level Dependence Features (SGLDF) and fractal textures are used to decipher the intrinsic structure of benign and malignant thyroid lesions. These features are subjected to graph based Marginal Fisher Analysis (MFA) to reduce the number of features. The reduced features are subjected to various ranking methods and classifiers. We have achieved an average accuracy, sensitivity and specificity of 97.52%, 90.32% and 98.57% respectively using Support Vector Machine (SVM) classifier. The achieved maximum Area Under Curve (AUC) is 0.9445. Finally, Thyroid Clinical Risk Index (TCRI) a single number is developed using two MFA features to discriminate the two classes. This prototype system is ready to be tested with huge diverse database.en_US
dc.subjectPhysics and Astronomyen_US
dc.titleFusion of spatial gray level dependency and fractal texture features for the characterization of thyroid lesionsen_US
article.volume77en_US Institute of Technologyen_US Ann Polytechnicen_US Institute of Managementen_US of Malayaen_US Prefectural Universityen_US di Torinoen_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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