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dc.contributor.authorBongkot Jia-Mahasapen_US
dc.contributor.authorImjai Chitapanaruxen_US
dc.contributor.authorEkkasit Tharavichitkulen_US
dc.contributor.authorSomvilai Chakrabandhuen_US
dc.contributor.authorPitchayaponne Klunklinen_US
dc.contributor.authorWimrak Onchanen_US
dc.contributor.authorAnirut Watcharawiphaen_US
dc.contributor.authorSomsak Wanwilairaten_US
dc.contributor.authorPatrinee Traisathiten_US
dc.description.abstract© 2017 Cambridge University Press. Purpose Craniospinal irradiation (CSI) has become an important and challenging radiation technique for radiation oncologists. Helical tomotherapy (HT) seems to have dosimetric advantage for CSI compared with other radiation modalities. The purpose of this study was to compare dosimetric data between two different HT plans; simultaneous integrated boost (SIB) and sequential boost (Sq). Method Twelve previously treated CSI contoured datasets by SIB technique were replanned. Dosimetric comparative parameters of targets were conformity index (CI) and homogeneity index (HI). For organ at risk (OARs), the mean dose of parallel organs, D2% of serial organs and whole body integral dose (ID) were also investigated. Result SIB plan significantly provided more conformed dose to CSI and tumour boost while resulting in a similar CI in spinal boost region compared with Sq plan. The HI showed no differences between two plans. Radiation exposure to serial organs and ID were also significantly lower in SIB plan. Conclusion CSI treatment using HT, SIB technique was feasible and had more target coverage while minimising the radiation dose to healthy tissues.en_US
dc.titleDosimetric comparison of helical tomotherapy using different techniques, simultaneous integrated boost and sequential boost for craniospinal irradiation: A single institution experienceen_US
article.title.sourcetitleJournal of Radiotherapy in Practiceen_US
article.volume16en_US of Medicine, Thammasat Universityen_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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