Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorBhagavathi Sundaram Sivamaruthien_US
dc.contributor.authorNoppawat Pengkumsrien_US
dc.contributor.authorManee Saeleeen_US
dc.contributor.authorPeriyanaina Kesikaen_US
dc.contributor.authorSasithorn Sirilunen_US
dc.contributor.authorSartjin Peerajanen_US
dc.contributor.authorChaiyavat Chaiyasuten_US
dc.description.abstract© 2016 The Authors. Published by Innovare Academic Sciences Pvt Ltd. Objective: The aim of the study was to evaluate the chemical stability and antioxidant ability of selected anthocyanidin (ACN) upon various commonly used physical treatments. Methods: Pure compounds of representative ACNs (cyanidin, peonidin) were subjected to microwave, heat, and sonication treatments followed by analyzing the rate of degradation by LC-MS. The changes in the antioxidant ability of ACNs were also assessed by DPPH and ABTS assay. Results: All the tested treatment strategies accelerated the degradation and diminished the antioxidant capacity of pure ACN, more specifically heat exposure cause ~ 90% of degradation and ∼3 fold reduction in antioxidant capacity. About 91.34% and 87.73% of cyanidin and peonidin degradation were documented after heat treatment, respectively. Relatively sonication has not accelerated the ACN debasement, but significant level of degradation (p<0.05) was observed. Conclusion: The study results suggested that the maximum concern is required for the selection of the method of the degerming process during the production of precious formulations. This study revealed that microwave and sonication processes are better than dry heat based aseptic methods for pure ACNs based product, especially in pharmaceuticals with respect to the stability and bioactivity of ACN.en_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleImpact of physical treatments on stability and radical scavenging capacity of anthocyanidinsen_US
article.title.sourcetitleInternational Journal of Pharmacy and Pharmaceutical Sciencesen_US
article.volume8en_US Mai Universityen_US Innovation Instituteen_US
Appears in Collections:CMUL: Journal Articles

Files in This Item:
There are no files associated with this item.

Items in CMUIR are protected by copyright, with all rights reserved, unless otherwise indicated.