Please use this identifier to cite or link to this item:
Title: Antibiotic resistance of Campylobacter jejuni and C. coli isolated from children with diarrhea in Thailand and Japan
Authors: Ngan Thi Kim Pham
Aksara Thongprachum
Dinh Nguyen Tran
Shuichi Nishimura
Yuko Shimizu-Onda
Quang Duy Trinh
Pattara Khamrin
Nuthapong Ukarapol
Tipachan Kongsricharoern
Shihoko Komine-Aizawa
Shoko Okitsu
Niwat Maneekarn
Satoshi Hayakawa
Hiroshi Ushijima
Keywords: Medicine
Issue Date: 21-Jan-2016
Abstract: © 2016, National Institute of Health. All rights reserved. A total of 29 Campylobacter jejuni and C. coli strains were isolated from Thai and Japanese children with diarrhea using the Loop-mediated Isothermal Amplification method. The samples were evaluated for mutations in gyrA and 23S rRNA in order to assess resistance against fluoroquinolones and macrolides, respectively. Among the isolated strains, 9 (8 C. jejuni and 1 C. coli) were from Thai children, and the other 20 (C. jejuni) were isolated from Japanese children. High fluoroquinolone resistance rates were observed in Thai (66.7%) and Japanese (90%) children. Macrolide resistance was not observed in Japanese children but was observed at a considerable rate of 12.5% of C. jejuni isolated in the Thai cohort. The results indicate that continuous monitoring of resistance of Campylobacter strains to fluoroquinolones and macrolides is definitely necessary.
ISSN: 18842836
Appears in Collections:CMUL: Journal Articles

Files in This Item:
There are no files associated with this item.

Items in CMUIR are protected by copyright, with all rights reserved, unless otherwise indicated.