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dc.contributor.authorSita Preedanonen_US
dc.contributor.authorSouwalak Phongpaichiten_US
dc.contributor.authorJariya Sakayarojen_US
dc.contributor.authorVatcharin Rukachaisirikulen_US
dc.contributor.authorNanthaphong Khamthongen_US
dc.contributor.authorKongkiat Trisuwanen_US
dc.contributor.authorSakanan Plathongen_US
dc.description.abstract© 2016, National Institute of Science Communication and Information Resources (NISCAIR). All rights reserved. One hundred and sixty-three fungi isolated from gorgonian sea fan Annella sp. were screened for antimicrobial activity against human pathogens. Forty-seven percents of the isolates produced antimicrobial metabolites against at least one pathogen with minimum inhibitory concentrations (MIC) ranged from 1 to 1,280 µg mL-1. Crude extracts from 16%, 21%, 18% and 23% of the isolates inhibited standard strain of Staphylococcus aureus, methicillin-resistant S. aureus, Escherichia coli and Pseudomonas aeruginosa, respectively. Eighteen percents of the isolates displayed antifungal activity against Microsporum gypseum while only 3% inhibited Cryptoccocus neoformans and Candida albicans. Potential isolates were identified by morphological and molecular characteristics. Twenty-nine pure compounds isolated from ten isolates were evaluated for antimicrobial activity. Griseofulvin from Nigrospora sp. PSU-F13 exhibited the best activity against M. gypseum (MIC 2 µg mL-1). The result indicates that sea fan-derived fungi are a potential source of antimicrobial agents.en_US
dc.subjectEarth and Planetary Sciencesen_US
dc.titleAntimicrobial activities of fungi derived from the gorgonian sea fan Annella sp. & their metabolitesen_US
article.title.sourcetitleIndian Journal of Geo-Marine Sciencesen_US
article.volume45en_US of Songkla Universityen_US National Center for Genetic Engineering and Biotechnologyen_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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