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Title: Metal-free amidation of carboxylic acids with tertiary amines
Authors: Wong Phakhodee
Sirilak Wangngae
Mookda Pattarawarapan
Keywords: Chemical Engineering
Issue Date: 1-Jan-2016
Abstract: © 2016 The Royal Society of Chemistry. A direct amidation of carboxylic acids with tertiary amines could be carried out in the presence of the Ph3P-I2 activator. With an appropriate reagent addition sequence, a range of carboxylic acids including aliphatic, allylic, and aromatic acids could be converted into their corresponding tertiary amides under mild conditions without requirement of metal catalysis.
ISSN: 20462069
Appears in Collections:CMUL: Journal Articles

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