Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/55376
Title: Transfollicular enhancement of methyl myristate loaded in cationic niosomes incorporated in hair lotion
Authors: Jiradej Manosroi
Charinya Chankhampan
Puxvadee Chaikul
Worapaka Manosroi
Aranya Manosroi
Keywords: Chemical Engineering
Chemistry
Pharmacology, Toxicology and Pharmaceutics
Issue Date: 17-Aug-2016
Abstract: © 2016 Informa UK Limited, trading as Taylor & Francis Group. Hair lotion containing methyl myristate loaded in cationic niosomes (HL-MMnio) composed of Brij72/cholesterol/DDAB at 7:3:0.65 molar ratio was developed. The remaining percentages of MM loaded in cationic niosomes in hair lotion were higher than free MM in hair lotion of about 1.2 times. The cumulative amounts in porcine skin and the receiver compartment of MM loaded in cationic niosomes incorporated in hair lotion were higher than those of free MM in hair lotion of 1.45 and 1.32 times, respectively. HL-MMnio showed very slightly irritation on rabbit skin, which was disappeared after 4 d. For melanogenesis induction in C57BL/6 mice with aged-induced grey body coat hairs, the highest pigmentation scores of HL-MMnio applied on the dorsal area were observed after 21 days, while hair lotion containing the free MM indicated after 35 days. This study has suggested that HL-MMnio was the high potential formulation for canities treatment.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84986197905&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/55376
ISSN: 14645246
02652048
Appears in Collections:CMUL: Journal Articles

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