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http://cmuir.cmu.ac.th/jspui/handle/6653943832/54817| Title: | Efavirenz concentrations and probability of HIV replication in children |
| Authors: | Nontiya Homkham Tim R. Cressey Naïm Bouazza Chulapong Chanta Linda Aurpibul Thition Narkbunnam Sawitree Krikajornkitti Nareerat Kamonpakorn Marc Lallemant Lily Ingsrisawang Nicolas Salvadori Jean Marc Treluyer Saik Urien Gonzague Jourdain |
| Authors: | Nontiya Homkham Tim R. Cressey Naïm Bouazza Chulapong Chanta Linda Aurpibul Thition Narkbunnam Sawitree Krikajornkitti Nareerat Kamonpakorn Marc Lallemant Lily Ingsrisawang Nicolas Salvadori Jean Marc Treluyer Saik Urien Gonzague Jourdain |
| Keywords: | Medicine |
| Issue Date: | 1-Jan-2015 |
| Abstract: | Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved. In 188 HIV-infected children receiving efavirenz, a lower middose (C12) was associated with a higher risk of HIV-1 viral load >400 copies/ mL (P = 0.03). Simulations for a normalized population receiving US Food and Drug Administration weight-band dosing predicted that 15% of children would have a C12 below target threshold (<1.0 mg/L) with a 23% risk of viral replication. |
| URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84944217669&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/54817 |
| ISSN: | 15320987 08913668 |
| Appears in Collections: | CMUL: Journal Articles |
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