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dc.contributor.authorEkarat Rattarittamrongen_US
dc.contributor.authorLalita Norasetthadaen_US
dc.contributor.authorAdisak Tantiworawiten_US
dc.contributor.authorChatree Chai-Adisaksophaen_US
dc.contributor.authorSasinee Hantrakoolen_US
dc.contributor.authorThanawat Rattanathammetheeen_US
dc.contributor.authorPimlak Charoenkwanen_US
dc.description.abstract© E. Rattarittamrong et al, 2015 Licensee PAGEPress, Italy. Thrombosis is a major complication of polycythemia vera (PV) and also a well-known complication of thalassemia. We reported a case of non-atherosclerotic ST-segment elevation myocardial infarction (STEMI) in a 17-year-old man with concurrent post-splenectomized hemoglobin H-Constant Spring disease and JAK2 V617F mutation-positive PV. The patient initially presented with extreme thrombocytosis (platelet counts greater than 1,000,000/μL) and three months later developed an acute STEMI. Coronary artery angiography revealed an acute clot in the right coronary artery without atherosclerotic plaque. He was treated with plateletpheresis, hydroxyurea and antiplatelet agents. The platelet count decreased and his symptoms improved. This case represents the importance of early diagnosis, awareness of the increased risk for thrombotic complications, and early treatment of PV in patients who have underlying thalassemia with marked thrombocytosis.en_US
dc.titleAcute non-atherosclerotic ST-segment elevation myocardial infarction in an adolescent with concurrent hemoglobin H-Constant Spring disease and polycythemia veraen_US
article.title.sourcetitleHematology Reportsen_US
article.volume7en_US of Hematologyen_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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