Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/53889
Title: Antibacterial Activity and Inhibition of Adherence of Streptococcus mutans by Propolis Electrospun Fibers
Authors: Chawalinee Asawahame
Krit Sutjarittangtham
Sukum Eitssayeam
Yingmanee Tragoolpua
Busaban Sirithunyalug
Jakkapan Sirithunyalug
Keywords: Pharmacology, Toxicology and Pharmaceutics
Issue Date: 1-Jan-2014
Abstract: © 2014, American Association of Pharmaceutical Scientists. Mouth-dissolving fibers with antibacterial activity for the oral cavity were prepared by an electrospinning technique. Propolis extract was used as an active ingredient and polyvinylpyrrolidone (PVP) K90 as the polymer matrix. The morphology and diameter of the fibers were characterized by scanning electron microscopy. Antibacterial activity against Streptococcus mutans and the inhibition of S. mutans adhesion on a smooth glass surface during the biofilm formation were tested. Propolis, 5% (w/v), was combined with a PVP K90 solution, 8% (w/v), with or without Tween 80 including flavor additives and electrospun with an applied voltage of 15 kV. Uniform and smooth fibers of propolis-PVP K90 were obtained. The results showed that electrospun fibers with propolis extract can dissolve and release the propolis in water. Propolis-PVP electrospun fibers showed better antibacterial activity by reduction of bacteria adhesion on a smooth glass surface when compared to some commercial mouthwash products. These results indicated the potential of electrospun fibers to be used as mouth-dissolving fibers for effective antibacterial activity in the oral cavity.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84925505780&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/53889
ISSN: 15309932
Appears in Collections:CMUL: Journal Articles

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