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dc.contributor.authorKanlaya Inseeen_US
dc.contributor.authorPeraphan Pothacharoenen_US
dc.contributor.authorPrachya Kongtawelerten_US
dc.contributor.authorSiriwan Ongchaien_US
dc.contributor.authorDhirawat Jotikasthiraen_US
dc.contributor.authorSuttichai Krisanaprakornkiten_US
dc.description.abstractThe aims of this study were to compare the chondroitin sulphate (CS) levels in gingival crevicular fluid (GCF) of moved canines using either 70 or 120g of orthodontic force, and to compare the rate of tooth movement and the amount of pain between these two force magnitudes. Sixteen patients (6 males and 10 females; aged 16.91±2.99 years), with class I malocclusion, who required orthodontic treatment with first premolar extractions, were recruited. The force magnitudes used to move the maxillary canines distally were controlled at 70 and 120g on the right and the left sides, respectively. GCF samples were collected with Periopaper®strips before and during orthodontic tooth movement. Competitive ELISA with monoclonal antibody was used to measure the CS levels. The distance of tooth movement and the amount of pain assessed by visual analog scale (VAS) scores were evaluated. The medians of CS levels during the loaded period were significantly greater than those during the unloaded period (P < 0.05). The differences between the medians of CS levels of 70g and 120g retraction force during each 1 week period were not significant. There was no significant difference in the rates of canine movement between these two force magnitudes. However, using 120g, the medians of VAS scores were significantly greater than those with 70g (P < 0.05). Collectively, 70g retraction force appears to be sufficient and more suitable than 120g force as it causes no difference in biochemically-assessed bone remodelling activity, the same rate of tooth movement, reduced pain and better comfort. © 2013 © The Author 2013. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved.en_US
dc.titleComparisons of the chondroitin sulphate levels in orthodontically moved canines and the clinical outcomes between two different force magnitudesen_US
article.title.sourcetitleEuropean Journal of Orthodonticsen_US
article.volume36en_US of Orthodontics and Pediatric Dentistryen_US of Excellence for Innovation in Chemistryen_US Mai Universityen_US
Appears in Collections:CMUL: Journal Articles

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