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Title: Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
Authors: Sarot Cheenpracha
Thunwadee Ritthiwigrom
Surat Laphookhieo
Keywords: Biochemistry, Genetics and Molecular Biology
Pharmacology, Toxicology and Pharmaceutics
Issue Date: 26-Apr-2013
Abstract: Chemical investigation of an alkaloidal extract of Alstonia macrophylla bark led to the isolation and identification of two new nitrogenous derivatives, alstoniaphyllines A (1) and B (2), a new indole alkaloid, alstoniaphylline C (4), and eight known alkaloids (3, 5-11). Alstonisine (9) exhibited antiplasmodial activity against Plasmodium falciparum, with an IC50 of 7.6 μM. © 2013 The American Chemical Society and American Society of Pharmacognosy.
ISSN: 15206025
Appears in Collections:CMUL: Journal Articles

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