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Title: | An alternative synthesis of (+) - propranolol and (+) atenolol |
Authors: | Rachaneebhorn Inkum Aphiwat Teerawutgulrag Pakawan Puangsombat Nuansri Rakariyatham |
Authors: | Rachaneebhorn Inkum Aphiwat Teerawutgulrag Pakawan Puangsombat Nuansri Rakariyatham |
Keywords: | Multidisciplinary |
Issue Date: | 1-Sep-2012 |
Abstract: | Herein, a simple synthesis pathway of beta-blockers starting from allyl amine is presented. This synthesis features the opening of an epoxide ring with phenol derivatives followed by N-alkylation with iso-propylbromide to produce racemic propranolol and atenolol. © 2012 by Maejo University, San Sai, Chiang Mai, 50290 Thailand. |
URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84867869116&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/52032 |
ISSN: | 19057873 |
Appears in Collections: | CMUL: Journal Articles |
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