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Title: Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
Authors: Sanchai Nayyatip
Pak Thaichana
Mongkol Buayairaksa
Wirote Tuntiwechapikul
Puttinan Meepowpan
Narong Nuntasaen
Wilart Pompimon
Keywords: Biochemistry, Genetics and Molecular Biology
Chemical Engineering
Computer Science
Issue Date: 1-Apr-2012
Abstract: A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, 1) together with the known alkaloid stigmalactam (2), were isolated from Orophea enterocarpa. Their structures were elucidated on the basis of interpretation of their spectroscopic data. Compounds 1 and 2 exhibited significant cytotoxicities against human colon adenocarcinoma (HCT15) cell line with IC50 values of 1.68 and 1.32 μM, respectively. © 2012 by the authors.
ISSN: 14220067
Appears in Collections:CMUL: Journal Articles

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