Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/50592
Title: Anti-inflammatory, analgesic, and antipyretic activities of virgin coconut oil
Authors: S. Intahphuak
P. Khonsung
A. Panthong
Keywords: Biochemistry, Genetics and Molecular Biology
Medicine
Pharmacology, Toxicology and Pharmaceutics
Issue Date: 12-Feb-2010
Abstract: This study investigated some pharmacological properties of virgin coconut oil (VCO), the natural pure oil from coconut [Cocos nucifera Linn (Palmae)] milk, which was prepared without using chemical or high-heat treatment. The anti-inflammatory, analgesic, and antipyretic effects of VCO were assessed. In acute inflammatory models, VCO showed moderate anti-inflammatory effects on ethyl phenylpropiolate-induced ear edema in rats, and carrageenin- and arachidonic acid-induced paw edema. VCO exhibited an inhibitory effect on chronic inflammation by reducing the transudative weight, granuloma formation, and serum alkaline phosphatase activity. VCO also showed a moderate analgesic effect on the acetic acid-induced writhing response as well as an antipyretic effect in yeast-induced hyperthermia. The results obtained suggest anti-inflammatory, analgesic, and antipyretic properties of VCO. © 2010 Informa UK Ltd.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=76149115555&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/50592
ISSN: 17445116
13880209
Appears in Collections:CMUL: Journal Articles

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