Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/4611
Title: Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract
Authors: Singhatong S.
Leelarungrayub D.
Chaiyasut C.
Issue Date: 2010
Abstract: The antioxidant activity of Artocarpus lakoocha heartwood extract was investigated from ethanol extraction by 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) decolorization, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and H2O2 scavenging assay. Polyphenolic; total phenolic, flavonoids and tannins were measured. Anti-oxidative stress was studied in AAPH-oxidized blood and glutathione (GSH), and malondialdehyde (MDA) was evaluated. Results showed that antioxidant activities were 128.30 ± 0.13, 55.86 ± 0.01, and 463.49 ± 0.01 μmol Trolox/g extracted from ABTS, DPPH, and H2O2 scavenging methods. One gram of extract contained total phenol (325.63 ± 2.99 mg GE), flavonoids (521.98 ± 0.01 mg QE) and tannins (124.03 ± 0.46 g TE), including rutin and resocinol. In the blood system, a low concentration of extract inhibited MDA progression and improved GSH, which was in contrast to a high concentration with its toxicity effect.
URI: http://www.scopus.com/inward/record.url?eid=2-s2.0-77954054479&partnerID=40&md5=d4e0db8d55654cdb5e90750234fae78e
http://cmuir.cmu.ac.th/handle/6653943832/4611
ISSN: 19960875
Appears in Collections:PHARMACY: Journal Articles

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