Please use this identifier to cite or link to this item: http://cmuir.cmu.ac.th/jspui/handle/6653943832/1742
Title: Molecular characterization of norovirus variants and genetic diversity of noroviruses and sapoviruses in Thailand
Authors: Chaimongkol N.
Khamrin P.
Malasao R.
Thongprachum A.
Kongsricharoern T.
Ukarapol N.
Ushijima H.
Maneekarn N.
Issue Date: 2014
Publisher: Wiley-Liss Inc.
Abstract: Norovirus (NoV) and Sapovirus (SaV) have been reported as a common cause of acute gastroenteritis worldwide. For a decade, surveillances of NoV and SaV have been conducted continually in Thailand. To monitor the epidemiological situation and to determine the genetic variation of NoV and SaV in Chiang Mai, Thailand, 567 samples collected from pediatric patients hospitalized with acute gastroenteritis were examined during 2007, and 2010-2011 by semi-nested RT-PCR and nucleotide sequencing methods. NoV was detected at 15.9%. Phylogenetic analysis revealed multiple NoV genotypes, GI/14 (1.1%), GII/1 (1.1%), GII/2 (1.1%), GII/3 (4.4%), GII/4 (65.6%), GII/6 (10.0%), GII/7 (2.2%), GII/12 (4.4%), GII/13 (3.3%), GII/16 (5.7%), and unclassified genotype (1.1%), circulating in this area. Among these, NoV GII/4 was the most prevalent genotype with a predominance of GII/4 2009 over other variants, 1996, 2006a, and 2006b. For SaV, the prevalence was 1.2% which was much lower than those of NoV and only SaV GI/1 was detected. This study highlights the epidemiology of NoV and SaV and genetic diversity of viruses circulating in pediatric patients hospitalized with acute gastroenteritis in Chiang Mai, Thailand. © 2013 Wiley Periodicals, Inc.
URI: http://www.scopus.com/inward/record.url?eid=2-s2.0-84899972352&partnerID=40&md5=5c1d26d24e49972580e3617ea633ba88
http://cmuir.cmu.ac.th/handle/6653943832/1742
ISSN: 10969071
Appears in Collections:MED: Journal Articles

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